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WebJun 1, 2024 · Spironolactone (Aldactone) is a type of medication known as an aldosterone receptor antagonist. It’s FDA-approved for treatment of fluid retention caused by a variety of conditions, including... WebTake this medication by mouth, as directed by your doctor. If stomach upset occurs, take it with food or milk. It is best to take your dose early in the day (before 6 p.m.) to prevent having to get...

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