Cyld antibody
WebApr 10, 2024 · CYLD is a deubiquitinating enzyme that plays a crucial role in immunity and inflammation as a negative regulator of NF-κB transcription factor and JNK kinase signaling. Defects in either of these pathways contribute to the progression of numerous inflammatory and autoimmune disorders. Therefore, we set out to unravel molecular mechanisms that … WebCYLD is identified as a tumor suppressor protein affecting the JNK signaling pathway. CYLD is a negative regulator of TRAF2 and NF-kappa-B signaling pathway and is also known to have receptor-dependent role in regulating the I-kappa-B kinase pathway.
Cyld antibody
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WebMar 11, 2016 · Cutaneous cylindroma is an adnexal tumour with apocrine differentiation. A predisposition to multiple cylindromas is seen in patients with Brooke–Spiegler syndrome, who carry germline mutations in the tumour suppressor gene CYLD.Previous studies of inherited cylindromas have highlighted the frequent presence of bi-allelic truncating … Web大鼠转化生长因子β2免费代测elisa试剂盒上海联祖生物相关产品:沼泽考克氏菌人抑制素b（inh-b）elisa试剂盒肝...
WebView Rabbit Polyclonal anti-CYLD Antibody (NBP2-92436). Validated Applications: WB, IHC, IHC-P. Validated Species: Human, Mouse, Rat. Sample size available. WebCYLD Antibodies . Target Information. CYLD is a 956 aa, cytoplasmic, deubiquitinating enzyme belonging to the ubiquitin carboxy-terminal hydrolases (UCH) family of proteins with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains, a proline rich region, a SH3 binding domain and a sequence homology to catalytic domain of ...
WebCYLD Modification Unmodified View Product On Supplier's Website Request a Quote from Cell Signaling Technology Supplier provided information Immunogen Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding His334 of human CYLD protein.
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WebWestern Blot: CYLD Antibody [NB100-78600] - Sample (30 ug of whole cell lysate) A: Hep G2 7. 5% SDS PAGE; antibody diluted at 1:1000. Immunocytochemistry/ Immunofluorescence: CYLD Antibody [NB100 … irs corporate tax filing datesWebCYLD (D1A10) Rabbit mAb recognizes endogenous levels of total CYLD protein. This antibody detects an unidentified protein of approximately 28 kDa in some cell types. Species Reactivity: Human, Mouse, Rat, Monkey … irs corporation loginWebImmunohistochemistry analysis of paraffin-embedded CYLD in human brain cancer tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with CYLD polyclonal antibody (Product # PA5-106325) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit. irs corporate tax paymentsWebCYLD is identified as a tumor suppressor protein affecting the JNK signaling pathway. CYLD is a negative regulator of TRAF2 and NF-kappa-B signaling pathway and is also … irs corporation filing deadline 2021WebMeanwhile, inhibition of CYLD did not affect the quality of antibody. Thus, our data demonstrated that inactivation of CYLD could promote CHO cell proliferation, anti-apoptosis ability, and subsequent antibody production, suggesting that CYLD is a potential functional target for CHO cell engineering. irs corporation informationWebThis CYLD antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a doublet is seen ~120 kDa (Hellerbrand, et al.) The observed molecular … portable starter chargerWebCYLD. The antibodies are designated mAB for monoclonal and pAb for polyclonal. The release of the Human Protein Atlas in which the antibody was first published. All assays through which the antibody has been validated. Assays&annotation provide a detailed description of the different assays. The pie-charts indicate degree of validation. portable stationary cycle