High-affinity choline uptake protein bett

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August undefined, 2024

WebThe initial step in the CDP-choline/Kennedy pathway is uptake of choline into cells by three classes of transporters: the high-affinity (K D 2 μM), sodium-coupled choline transporter 1 (CHT1 or SLC5A7); intermediate-affinity (K D 10–100 μM), sodium-independent choline transporter-like (CTL) proteins of the SLC44A family; and low … Web1 de abr. de 2024 · Furthermore, the genome contains nine genes related to the synthesis and transport of the compatible-solute glycine betaine for resistance to osmotic stress …

Choline Uptake - an overview ScienceDirect Topics

Web1 de mai. de 2008 · This transporter has a particularly low affinity (Km of 876 μM) and high capacity (Vmax of 80 nmol/min/mg of protein) for choline transport relative to other … WebHigh-affinity transport of choline-O-sulfate and its use as a compatible solute in Bacillus subtilis High-affinity transport of choline-O-sulfate and its use as a compatible solute in … reacstick

The High-Affinity Choline Uptake System SpringerLink

WebIn cholinergic neurons, high-affinity choline uptake in presynaptic terminals is the rate-limiting step in acetylcholine synthesis. Using information provided by the … WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules) Web3 de mar. de 2024 · The betT gene encodes the high-affinity choline uptake protein BetT, betI encodes the choline-responsive BetI repressor for both choline uptake and betaine synthesis (Scholz et al. 2016), and opuA is … how to start a weber

ADILRU_1989 - High-affinity choline uptake protein BetT

Competitive inhibition of the high-affinity choline transporter by ...

Web29 de jul. de 2014 · The high-affinity choline uptake activity was also shown to depend on the kind of anions and on the concentrations of K +: the highest activity was observed in the presence of Cl − and 0.35–4.8 mM K +, together with 126 mM Na + . Selective distribution and characterization of the high-affinity choline uptake system in cholinergic neurons WebThe presumed binding proteins of both ABC transporters were shown to be lipoproteins. ... -choline uptake via OpuB (K(m) = 1 microM; Vmax = 21 nmol min-1 mg-1 protein) and OpuC (K(m) = 38 microM; Vmax = 75 nmol min-1 mg-1 protein) revealed that each of these ABC transporters exhibits high affinity and substantial transport capacity. how to start a webex webinarWebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. Proteomes. Protein sets from fully sequenced genomes. Annotation systems. Systems used to automatically annotate proteins with high accuracy: UniRule (Expertly curated rules) how to start a website blog

"Web25 de mar. de 2024 · Choline uptake and LPS decoration protects bacteria from osmotic pressure, and enables avoiding the immune system recognition. Choline uptake is provided in P. mirabilis O18 by a high-affinity choline transport protein BetT. Choline gained in this way is involved in the glycine betaine biosynthesis pathway, ... " - High-affinity choline uptake protein bett

High-affinity choline uptake protein bett

Characteristics of (3H)‐choline uptake into synaptosomes from rat ...

Webmax of 80 nmol/min/mg of protein) for choline transport relative to other known BCCTs. Although BetT activity increased in response to hyperosmolarity, BetT mediated signiﬁcant uptake under low ... Web1 de mar. de 2007 · For osmoprotection, Escherichia coli can synthesize glycine betaine from externally supplied choline by the Bet system (betTIBA products). The major carrier of choline is the high-affinity, proton-driven, secondary transporter BetT, which belongs to the BCCT family of transporters. Fusion proteins consisting of N-terminal fragments of …

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Web23 de dez. de 2009 · We identified a choline, betaine and carnitine transporter, designated Cbc, from Pseudomonas syringae and Pseudomonas aeruginosa that is unusual among members of the ATP-binding cassette (ABC) transporter family in its use of multiple periplasmic substrate-binding proteins (SBPs) that are highly specific for their … WebE. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA …

WebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. … WebGene ID: 13909447, discontinued on 16-Jul-2024. Summary Other designations. High-affinity choline uptake protein BetT

Web16 de mai. de 2013 · High-affinity choline uptake protein BetT: Tetragenococcus halophilus: 12172: TEH_13620: glycine betaine transporter ButA: Thauera linaloolentis: 102519: C666_13385: choline/carnitine/betaine transporter: Tsukamurella paurometabola: 16120: Tpau_2792: choline/carnitine/betaine transporter: WebThe nature of the high affinity uptake system guarantees that cholinergic cells will always receive priority access to all available choline. Because of this, choline will be …

WebCholine uptake (Vmax) increases up to 3 months of age and decreases significantly from 1 to 7 years of age ( Fig. 6A; Table III ). A further indication of a reduced synthesis with …

Web1 de jan. de 2024 · CHT1 has been functionally characterized by its capacity to transport choline with high affinity when expressed in cultured cells or Xenopus oocytes. CHT1 transports choline with a Km value of 1–5 μM in a Na + - and Cl −-dependent manner (Okuda et al. 2000).The only known specific inhibitor of CHT1 is hemicholinium-3 (HC-3), … how to start a website for free for kidsWebCholine uptake High affinity Na+-dependent Synaptosomes Certain basic characteristics of choline uptake in nerve terminals were ... protein, 0,567 uM [3H]-choline (final concentration), for 20 min at 371. The KM value of [3H]-choline uptake was 2.27+0.26 10 20 30 40 Time (min) 60 B I reacquire australian citizenshipWeb1 de jan. de 2024 · The high-affinity choline uptake activity in patients with these diseases was predicted to be diminished by mutations that impaired CHT1 function and/or trafficking. There is a functionally relevant, nonsynonymous single nucleotide polymorphism in the coding region of the human CHT1 gene (c.265A>G, rs1013940) (Okuda et al. 2002 ). how to start a webinarWebMeyer EM, Cooper JR (1983) High affinity choline uptake and calcium-dependent acetylcholine release in proteoliposomes derived from rat cortical synaptosomes. J … react + nprogressWebIn addition to the industrial and biomedical applications of lithium, information on the tolerance of microorganisms to high Li concentrations in natural biological systems is limited. Strain LCHXa is a novel free-living Gram-positive, non-motile how to start a website for free for businessWebProtein knowledgebase. UniParc. Sequence archive. Help. Help pages, FAQs, UniProtKB manual, documents, news archive and Biocuration projects. UniRef. Sequence clusters. … how to start a webexWebactivity increased in response to hyperosmolarity, BetT mediated signiﬁcant uptake under low-osmolarity conditions, suggesting a role in transport for both osmoprotection … react + express